Extended GO from the version of 20040601

    aging
          cell aging
             age-dependent general metabolic decline
                age-dependent general metabolic decline during chronological cell aging
                   age-dependent response to oxidative stress during chronological cell aging
                      age-dependent response to reactive oxygen species during chronological cell aging
                         accumulation of oxidatively modified proteins during chronological cell aging
                         age-dependent response to oxygen radicals during chronological cell aging
                         age-dependent response to singlet oxygen during chronological cell aging
                         age-dependent response to hydrogen peroxide during chronological cell aging
                      age-dependent response to lipid hydroperoxide during chronological cell aging
                age-dependent general metabolic decline during replicative cell aging
                   age-dependent response to oxidative stress during replicative cell aging
                      age-dependent response to reactive oxygen species during replicative cell aging
                         accumulation of oxidatively modified proteins during replicative cell aging
                            formation of oxidatively modified proteins during replicative cell aging
                               formation of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                            inheritance of oxidatively modified proteins during replicative cell aging
                               inheritance of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                            accumulation of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                         age-dependent response to oxygen radicals during replicative cell aging
                         age-dependent response to singlet oxygen during replicative cell aging
                         age-dependent response to hydrogen peroxide during replicative cell aging
                         age-dependent response to reactive oxygen species during nucleolar fragmentation during replicative aging
                      age-dependent response to lipid hydroperoxide during replicative cell aging
                      age-dependent response to oxidative stress during nucleolar fragmentation during replicative aging
                   age-dependent general metabolic decline during nucleolar fragmentation during replicative aging
                age-dependent response to oxidative stress
                   age-dependent response to oxidative stress during chronological cell aging
                      age-dependent response to reactive oxygen species during chronological cell aging
                         accumulation of oxidatively modified proteins during chronological cell aging
                         age-dependent response to oxygen radicals during chronological cell aging
                         age-dependent response to singlet oxygen during chronological cell aging
                         age-dependent response to hydrogen peroxide during chronological cell aging
                      age-dependent response to lipid hydroperoxide during chronological cell aging
                   age-dependent response to oxidative stress during replicative cell aging
                      age-dependent response to reactive oxygen species during replicative cell aging
                         accumulation of oxidatively modified proteins during replicative cell aging
                            formation of oxidatively modified proteins during replicative cell aging
                               formation of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                            inheritance of oxidatively modified proteins during replicative cell aging
                               inheritance of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                            accumulation of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                         age-dependent response to oxygen radicals during replicative cell aging
                         age-dependent response to singlet oxygen during replicative cell aging
                         age-dependent response to hydrogen peroxide during replicative cell aging
                         age-dependent response to reactive oxygen species during nucleolar fragmentation during replicative aging
                      age-dependent response to lipid hydroperoxide during replicative cell aging
                      age-dependent response to oxidative stress during nucleolar fragmentation during replicative aging
                   age-dependent response to lipid hydroperoxide
                   age-dependent response to reactive oxygen species
             chronological cell aging
                age-dependent general metabolic decline during chronological cell aging
                   age-dependent response to oxidative stress during chronological cell aging
                      age-dependent response to reactive oxygen species during chronological cell aging
                         accumulation of oxidatively modified proteins during chronological cell aging
                         age-dependent response to oxygen radicals during chronological cell aging
                         age-dependent response to singlet oxygen during chronological cell aging
                         age-dependent response to hydrogen peroxide during chronological cell aging
                      age-dependent response to lipid hydroperoxide during chronological cell aging
                progressive alteration of chromatin during chronological cell aging
                   loss of chromatin silencing during chronological cell aging
                   extrachromosomal circular DNA accumulation during chronological cell aging
             nucleolar fragmentation
                nucleolar fragmentation during replicative aging
             progressive alteration of chromatin during cell aging
                extrachromosomal circular DNA accumulation during cell aging
                   extrachromosomal circular DNA accumulation during replicative cell aging
                      extrachromosomal rDNA circle accumulation during replicative cell aging
                         formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                            formation of extrachromosomal circular rDNA by homologous recombination during nucleolar fragmentation during replicative aging
                         replication of extrachromosomal rDNA circles during replicative cell aging
                            replication of extrachromosomal rDNA circles during nucleolar fragmentation during replicative aging
                         extrachromosomal rDNA circle accumulation during nucleolar fragmentation during replicative aging
                      formation of extrachromosomal circular DNA during replicative cell aging
                         formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                            formation of extrachromosomal circular rDNA by homologous recombination during nucleolar fragmentation during replicative aging
                         formation of 2-micrometer circle DNA during replicative cell aging
                         formation of extrachromosomal rDNA circle during replicative cell aging
                         formation of extrachromosomal rDNA circles during replicative cell aging
                         formation of extrachromosomal circular DNA during nucleolar fragmentation during replicative aging
                      replication of extrachromosomal circular DNA during replicative cell aging
                         replication of extrachromosomal rDNA circles during replicative cell aging
                            replication of extrachromosomal rDNA circles during nucleolar fragmentation during replicative aging
                         replication of 2-micrometer circle DNA during replicative cell aging
                         replication of extrachromosomal rDNA circle during replicative cell aging
                         replication of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                         replication of extrachromosomal circular DNA during nucleolar fragmentation during replicative aging
                      2-micrometer circle DNA accumulation during replicative cell aging
                      extrachromosomal rDNA circles accumulation during replicative cell aging
                      extrachromosomal circular rDNA by homologous recombination accumulation during replicative cell aging
                      extrachromosomal circular DNA accumulation during nucleolar fragmentation during replicative aging
                   2-micrometer circle DNA accumulation during cell aging
                   extrachromosomal rDNA circle accumulation during cell aging
                   extrachromosomal rDNA circles accumulation during cell aging
                   replication of extrachromosomal circular DNA during cell aging
                   formation of extrachromosomal circular DNA during cell aging
                   extrachromosomal circular rDNA by homologous recombination accumulation during cell aging
                   extrachromosomal circular DNA accumulation during chronological cell aging
                progressive alteration of chromatin during chronological cell aging
                   loss of chromatin silencing during chronological cell aging
                   extrachromosomal circular DNA accumulation during chronological cell aging
                progressive alteration of chromatin during replicative cell aging
                   age-dependent telomere shortening
                   extrachromosomal circular DNA accumulation during replicative cell aging
                      extrachromosomal rDNA circle accumulation during replicative cell aging
                         formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                            formation of extrachromosomal circular rDNA by homologous recombination during nucleolar fragmentation during replicative aging
                         replication of extrachromosomal rDNA circles during replicative cell aging
                            replication of extrachromosomal rDNA circles during nucleolar fragmentation during replicative aging
                         extrachromosomal rDNA circle accumulation during nucleolar fragmentation during replicative aging
                      formation of extrachromosomal circular DNA during replicative cell aging
                         formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                            formation of extrachromosomal circular rDNA by homologous recombination during nucleolar fragmentation during replicative aging
                         formation of 2-micrometer circle DNA during replicative cell aging
                         formation of extrachromosomal rDNA circle during replicative cell aging
                         formation of extrachromosomal rDNA circles during replicative cell aging
                         formation of extrachromosomal circular DNA during nucleolar fragmentation during replicative aging
                      replication of extrachromosomal circular DNA during replicative cell aging
                         replication of extrachromosomal rDNA circles during replicative cell aging
                            replication of extrachromosomal rDNA circles during nucleolar fragmentation during replicative aging
                         replication of 2-micrometer circle DNA during replicative cell aging
                         replication of extrachromosomal rDNA circle during replicative cell aging
                         replication of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                         replication of extrachromosomal circular DNA during nucleolar fragmentation during replicative aging
                      2-micrometer circle DNA accumulation during replicative cell aging
                      extrachromosomal rDNA circles accumulation during replicative cell aging
                      extrachromosomal circular rDNA by homologous recombination accumulation during replicative cell aging
                      extrachromosomal circular DNA accumulation during nucleolar fragmentation during replicative aging
                   loss of chromatin silencing during replicative cell aging
                      loss of chromatin silencing during nucleolar fragmentation during replicative aging
                   progressive alteration of chromatin during nucleolar fragmentation during replicative aging
                loss of chromatin silencing during cell aging
             replicative cell aging
                age-dependent general metabolic decline during replicative cell aging
                   age-dependent response to oxidative stress during replicative cell aging
                      age-dependent response to reactive oxygen species during replicative cell aging
                         accumulation of oxidatively modified proteins during replicative cell aging
                            formation of oxidatively modified proteins during replicative cell aging
                               formation of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                            inheritance of oxidatively modified proteins during replicative cell aging
                               inheritance of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                            accumulation of oxidatively modified proteins during nucleolar fragmentation during replicative aging
                         age-dependent response to oxygen radicals during replicative cell aging
                         age-dependent response to singlet oxygen during replicative cell aging
                         age-dependent response to hydrogen peroxide during replicative cell aging
                         age-dependent response to reactive oxygen species during nucleolar fragmentation during replicative aging
                      age-dependent response to lipid hydroperoxide during replicative cell aging
                      age-dependent response to oxidative stress during nucleolar fragmentation during replicative aging
                   age-dependent general metabolic decline during nucleolar fragmentation during replicative aging
                nucleolar fragmentation during replicative aging
                progressive alteration of chromatin during replicative cell aging
                   age-dependent telomere shortening
                   extrachromosomal circular DNA accumulation during replicative cell aging
                      extrachromosomal rDNA circle accumulation during replicative cell aging
                         formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                            formation of extrachromosomal circular rDNA by homologous recombination during nucleolar fragmentation during replicative aging
                         replication of extrachromosomal rDNA circles during replicative cell aging
                            replication of extrachromosomal rDNA circles during nucleolar fragmentation during replicative aging
                         extrachromosomal rDNA circle accumulation during nucleolar fragmentation during replicative aging
                      formation of extrachromosomal circular DNA during replicative cell aging
                         formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                            formation of extrachromosomal circular rDNA by homologous recombination during nucleolar fragmentation during replicative aging
                         formation of 2-micrometer circle DNA during replicative cell aging
                         formation of extrachromosomal rDNA circle during replicative cell aging
                         formation of extrachromosomal rDNA circles during replicative cell aging
                         formation of extrachromosomal circular DNA during nucleolar fragmentation during replicative aging
                      replication of extrachromosomal circular DNA during replicative cell aging
                         replication of extrachromosomal rDNA circles during replicative cell aging
                            replication of extrachromosomal rDNA circles during nucleolar fragmentation during replicative aging
                         replication of 2-micrometer circle DNA during replicative cell aging
                         replication of extrachromosomal rDNA circle during replicative cell aging
                         replication of extrachromosomal circular rDNA by homologous recombination during replicative cell aging
                         replication of extrachromosomal circular DNA during nucleolar fragmentation during replicative aging
                      2-micrometer circle DNA accumulation during replicative cell aging
                      extrachromosomal rDNA circles accumulation during replicative cell aging
                      extrachromosomal circular rDNA by homologous recombination accumulation during replicative cell aging
                      extrachromosomal circular DNA accumulation during nucleolar fragmentation during replicative aging
                   loss of chromatin silencing during replicative cell aging
                      loss of chromatin silencing during nucleolar fragmentation during replicative aging
                   progressive alteration of chromatin during nucleolar fragmentation during replicative aging
          determination of adult life span
             zygotic determination of adult life span
             maternal determination of adult life span
          menopause
          senescence (sensu Magnoliophyta)
             leaf senescence