| PMID |
Curator |
System |
Sentence |
| 15126629 |
Yes |
Yes |
APC/C mutants were defective in metaphase/anaphase transition, whereas single scn mutants showed the delay in anaphase spindle elongation at 20 degrees C. |
| 15075284 |
Yes |
Yes |
Dual-Color imaging of nuclear division and mitotic spindle elongation in live cells of Aspergillus nidulans. |
| 14657278 |
Yes |
Yes |
We show that loss of nimU function leads to premature mitotic spindle elongation, premature mitotic exit, errors in chromosome segregation, and failure to delay mitotic exit under conditions that normally evoke the mitotic spindle checkpoint response. |
| 14657278 |
Yes |
Yes |
Whereas premature mitotic exit is dependent upon anaphase promoting complex function, premature spindle elongation is not. |
| 14534135 |
Yes |
No |
In C. elegans embryos, homologs of receptor-independent G protein activators, GPR-1 and GPR-2 (GPR-1/2), function together with Galpha (GOA-1 and GPA-16) to generate asymmetric spindle pole elongation during divisions in the P lineage. |
| 14534135 |
Yes |
Yes |
Furthermore, in addition to its involvement in spindle elongation, Galpha is required for the intrinsically programmed nuclear rotation event that orients the spindle in the one-cell. |
| 14534135 |
Yes |
Yes |
LET-99 functions antagonistically to the Galpha/GPR-1/2 signaling pathway, providing an explanation for how Galpha-dependent force is regulated asymmetrically by PAR polarity cues during both nuclear rotation and anaphase spindle elongation. |
| 12972644 |
Yes |
Yes |
In mitotic cells, a portion of the mitochondria was tethered to the spindle-pole bodies and moved to the cellular ends during spindle elongation. |
| 12972644 |
Yes |
Yes |
Thus, in contrast to kinesin-mediated transport used by higher eukaryotes, mitochondrial motility and distribution in fission yeast are driven largely by microtubule polymerization and the elongation of the mitotic spindle. |
| 12956950 |
Yes |
Yes |
We find that tac-1 is essential for pronuclear migration and spindle elongation in one-cell-stage C. elegans embryos. |
| 12802083 |
Yes |
Yes |
GFP-tagged CaCdc5p localized to unseparated spindle pole bodies, the spindle, and chromatin, consistent with a role in spindle elongation at an earlier point in the cell cycle than that described for the homologue Cdc5p in yeast. |
| 12802083 |
Yes |
Yes |
Similar defects in spindle elongation and a corresponding induction of filaments occurred when yeast cells were exposed to hydroxyurea. |
| 12658461 |
Yes |
Yes |
bservation of griseofulvin-treated T. vaginalis cells revealed that the elongation of the mitotic spindle or paradesmosis was not the main motile force separating the daughter kinetids to opposite poles during division, suggesting the existence of other mechanisms and/or molecules involved in this morphogenetic event. |
| 12636915 |
Yes |
Yes |
Reduction of the extent of spindle elongation or disruption of the central spindle causes delayed formation of the cleavage furrow. |
| 12591913 |
Yes |
Yes |
The midzone is the domain of the mitotic spindle that maintains spindle bipolarity during anaphase and generates forces required for spindle elongation (anaphase B). |
| 12591913 |
Yes |
Yes |
Furthermore, when overexpressed, Ase1p was sufficient to trigger spindle elongation in S phase-arrested cells. |