| PMID |
Curator |
System |
Sentence |
| 12466197 |
Yes |
Yes |
Development of the Drosophila genital disc requires interactions between its segmental primordia. |
| 12466197 |
Yes |
Yes |
Furthermore, cell ablation experiments show that the presence of all primordia (either the anal or the genital primordium) during development are required for normal development of genital disc. |
| 12466197 |
Yes |
Yes |
Collectively, these findings suggest that interaction between segmental primordia is required for the normal development of the genital disc. |
| 11702781 |
Yes |
Yes |
The classical view of genital disc development is that in each sex, dsx autonomously "represses" the development of the inappropriate genital primordium while allowing the development of the appropriate primordium. |
| 11494318 |
Yes |
Yes |
The development of the Drosophila genital disc. |
| 11494318 |
No |
Yes |
Therefore, the genital disc is a very good experimental model of how the sex-determination and homeotic genes - which determine cell identity - interact to direct the development of a population of cells into male or female terminalia. |
| 11494318 |
Yes |
Yes |
It has been proposed that the sexually dimorphic development of the genital disc is the result of an integrated genetic input, made up by the sex-determination gene doublesex and the homeotic gene Abdominal-B. |
| 11290302 |
No |
Yes |
We show that the gene dachshund (dac) is differentially expressed in the male and female genital discs, and plays sex-specific roles in the development of the genitalia. |
| 11245569 |
Yes |
Yes |
Sex determination genes control the development of the Drosophila genital disc, modulating the response to Hedgehog, Wingless and Decapentaplegic signals. |
| 11152632 |
Yes |
No |
The Hox gene Abdominal-B antagonizes appendage development in the genital disc of Drosophila. |
| 10446270 |
No |
No |
This study reports the expression pattern of Dll in the genital disc, the requirement of Dll activity for the development of the terminalia and the activation of Dll by the combined action of the morphogenetic signals Wingless (Wg) and Decapentaplegic (Dpp). |
| 9799432 |
Yes |
Yes |
We have analysed the roles of these genes in organising the development and differentiation of the genital discs, which are bilaterally symmetrical and possess different primordia, namely, the male and female genital primordia and an anal primordium. |
| 9799432 |
Yes |
Yes |
Our results suggest that the organising activity of en in genital discs programs the normal development and differentiation of the genital disc by regulating the expression of hh. |
| 7790349 |
Yes |
Yes |
A strong reduction in the expression of oho31 by a P element inserted in the 5' untranslated region of the oho31 transcript or a complete inactivation of oho31 by imprecise P element excision leads to malignant development of the hematopoietic organs and the genital disc, as shown by their growth autonomy in transplantation assays. |
| 7700356 |
No |
Yes |
The Abdominal B (AbdB) genes constitute a distinct subfamily of homeobox genes that exhibit posterior domains of expression, including the genital imaginal disc in Drosophila and the developing urogenital system in vertebrates. |